Primary Identifier | MGI:5603602 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Wwtr1 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | C57BL/6N-A<tm1Brd> | Is Recombinase | false |
Is Wild Type | false | Project Collection | EUCOMM |
molecularNote | This conditional allele, in which exon 3 is flanked by loxP sequences, was derived from the knockout-first Wwtr1tm1a(EUCOMM)Wtsi allele by flp recombinase-mediated excision of the lacZ reporter and the neomycin selection cassette. Cre recombinase expression will result in a knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. |