Primary Identifier | MGI:5604131 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Hand1 |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Residues T107 and S109 were replaced with aspartic acids. A Stop-flox cassette containing a neomycin resistance gene was also inserted downstream of the Hand1 transcriptional start site, but upstream of the Hand1-initiating methionine. Cre-excision of the stop cassette results in expression of the mutant. |