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Allele : Atg16l1<tm1.1Mvlc> autophagy related 16 like 1; targeted mutation 1.1, Menno van Lookeren Campagne
Primary Identifier  MGI:5605964 Allele Type  Targeted
Attribute String  Hypomorph Gene  Atg16l1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A T316A (ACT(Thr)-GCT(Ala)) mutation was introduced into exon 9 and an FRT flanked neo cassette was inserted in intron 9 via homologous recombination. Flp mediated recombination removed the neo cassette. Mutant protein cleavage is increased compared to the wild-type protein.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • T316A,
  • T316A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

8 Publication categories

Trail: Allele




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