| Primary Identifier | MGI:5606060 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Prnp |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd-Hprt1<b-m3> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The third exon was replaced with an enhanced GFP gene. Quantitative real-time PCR confirmed absence of Prnp mRNA in homozygotes and lower levels, about 50-60% that of wild-type, in heterozygotes. GFP expression was confirmed in various regions of the brain and in astrocytes. |
