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Allele : Nr5a2<tm3.1Sjns> nuclear receptor subfamily 5, group A, member 2; targeted mutation 3.1, Kristina Schoonjans
Primary Identifier  MGI:5607404 Allele Type  Targeted
Gene  Nr5a2 Transmission  Germline
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 6 was replaced with a modified exon 6 in which a point mutation (AAG to AGG) results in the amino acid substitution of arginine for lysine at position 289 (K289R) and a floxed neo cassette. Cre-mediated recombination removed the neo cassette. This mutation abolishes SUMOylation of Nr5a2.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Lrh-1 K289R,
  • Lrh-1 K289R
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele




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