Primary Identifier | MGI:5613106 | Allele Type | Targeted |
Attribute String | Conditional ready, Inducible, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Induced With | tamoxifen | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A cassette was inserted into the locus consisting of the CAG promoter, intron, floxed stop sequence, mouse Foxn1 cDNA fused to an ERT2 element, an IRES, and a GFP sequence. Cre mediated recombination is needed to induce protein expression. Protein activity in the presence of tamoxifen is similar to the endogenous protein. |