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Allele : Ripk3<tm1Arte> receptor-interacting serine-threonine kinase 3; targeted mutation 1, TaconicArtemis

Primary Identifier  MGI:5614565 Allele Type  Targeted
Attribute String  Conditional ready, Null/knockout Gene  Ripk3
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  A GAT to AAT mutation was inserted in exon 4 resulting in the replacement of aspartic acid at position 161 by asparagine (D161N). A loxP-Stop-loxP (LSL) transcription termination cassette was inserted in intron 3. The LSL cassette can be removed via cre-mediated recombination which results in expression of the D161N mutant allele.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Ripk3<LSL>,
  • Ripk3<LSL>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele