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Allele : Etv6<em3Knic> ets variant 6; endonuclease-mediated mutation 3, Kim E Nichols

Primary Identifier  MGI:7568839 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Null/knockout Gene  Etv6
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Arginine codon 355 (CGA) in exon 6 was changed to a stop codon (TGA) (p.R355*) using an sgRNA and an ssODN template with CRISP/Cas9 technology. The mutation is the equivalent of the human p.R359* mutation associated with thrombocytopenia 5 (T5).
  • mutations:
  • Single point mutation
  • synonyms:
  • Etv6<R355X>,
  • Etv6<R355X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele