| Primary Identifier | MGI:5621025 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Crx |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 4 was modified by nucleotide substitutions (CGT to TGG) that result in the amino acid substitution of tryptophan for arginine at position 90 (R90W) in the DNA binding domain, mimicking a mutation associated with the autosomal dominant form of cone-rod dystrophy (adCoRD) and with autosomal recessive Leber Congenital Amaurosis (LCA). Cre-mediated recombination removed the floxed allele inserted upstream of exon 4. |
