Primary Identifier | MGI:5621048 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Prnp-FUS)17Ljh |
Strain of Origin | (C57BL/6 x SJL)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains a cDNA sequence encoding the wild-type human fused in sarcoma protein (FUS). The cDNA sequence is inserted between exon 2 and exon 3 of mouse prion protein (PrP or Prnp) gene. Line PWT17 is identified with ~2 copies of the transgene and results in a 2-fold FUS overexpression. |