Primary Identifier | MGI:5633960 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence, Reporter | Gene | Tg(H-2K1-Lrp5/Fkbp1a,-luc*)#Dmps |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The H-2Kb promoter drives expression of the cytoplasmic portion of Lrp5 fused to two tandem AP20187 drug binding domains for chemically induced dimerization and the click beetle red-shifted luciferase gene. qRT-PCR confirmed expression of the transgene in multiple tissues of adults, with highest expression in the pancreas, followed by testes, mammary gland, spleen and prostate. |