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Allele : Tg(Lck-Ppp3ca*)28Naka transgene insertion 28, Toshinori Nakayama

Primary Identifier  MGI:5635497 Allele Type  Transgenic
Attribute String  Dominant negative, Inserted expressed sequence Gene  Tg(Lck-Ppp3ca*)28Naka
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene expresses a dominant negative mutated form of Ppp3ca under the control of the Lck proximal promoter. Sequence encoding five amino acid residues in the phosphatase active site (148-52) was deleted. Three transgenic lines were established. Line 28 expresses 50 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • dnCN Tg,
  • dnCN Tg
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele