Primary Identifier | MGI:5635497 | Allele Type | Transgenic |
Attribute String | Dominant negative, Inserted expressed sequence | Gene | Tg(Lck-Ppp3ca*)28Naka |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene expresses a dominant negative mutated form of Ppp3ca under the control of the Lck proximal promoter. Sequence encoding five amino acid residues in the phosphatase active site (148-52) was deleted. Three transgenic lines were established. Line 28 expresses 50 copies of the transgene. |