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Allele : Ephx2<tm2.1Arte> epoxide hydrolase 2, cytoplasmic; targeted mutation 2.1, TaconicArtemis
Primary Identifier  MGI:5636595 Allele Type  Targeted
Attribute String  Not Specified Gene  Ephx2
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A Cys521Ser substitution was introduced into exon 18 by changing a TGT codon to a TCC codon and an F3 flanked puro selection cassette was introduced into intron 16 via homologous recombination. Flp mediated recombination removed the selection cassette. This mutation prevents hydrolysis of the enzyme's epoxyeicosatrienoic acid (EET) substrates.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Cys521Ser,
  • Cys521Ser
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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