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Allele : Vwf<tm2.1Diac> Von Willebrand factor; targeted mutation 2.1, Thomas G Diacovo
Primary Identifier  MGI:5637366 Allele Type  Targeted
Attribute String  Not Specified Gene  Vwf
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A guanine to adenine at position 3925 (ATC>GTC) and adenine at position 3977 instead of guanine (CGT>CAT) were introduced in exon 28 to create the I1309V and R1325H mutations. In addition, a floxed pGK-Neo cassette was inserted downstream of exon 28 which was removed via cre-mediated excision.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • VWF<I1309V, R1326H>,
  • VWF<I1309V, R1326H>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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