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Allele : App<tm1.1Tcs> amyloid beta precursor protein; targeted mutation 1.1, Takaomi C Saido
Primary Identifier  MGI:5637815 Allele Type  Targeted
Attribute String  Humanized sequence Gene  App
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
molecularNote  The sequence of exon 16 was humanized by the introduction of the Swedish mutations (p.KM670_671delinsNL) and a loxP site flanked neomycin resistance gene cassette was inserted in intron 16. Subsequent Cre-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • App<NL>,
  • App<NL>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

18 Publication categories

Trail: Allele




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