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Allele : Tg(Rho*)2PRieke transgene insertion 2P, Fred Rieke
Primary Identifier  MGI:5640778 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Rho*)2PRieke
Strain of Origin  (C57BL/6J x DBA/2J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene expresses mouse Rho carrying only the S334 and S338 phosphorylation sites. The remaining phosphorylation sites in the Rho transgene (T336, T340, T342 and S343) are inactivated via serine or threonine to alanine mutations. An A337V mutation was introduced to confer a linear epitope for mAb3A6, that allows specific recognition of transgenic versus endogenous opsin.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • S334/S338/CSM,
  • S334/S338/CSM,
  • 2P,
  • 2P
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele




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