| Primary Identifier | MGI:5638883 | Allele Type | Targeted |
| Gene | Rb1 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A codon change from TTT to GCT introduced the amino acid substitution of alanine for phenylalanine at position 832 (F832A) in exon 24. A loxP-flanked PGK-Neo cassette was inserted downstream of the mutation and was removed via Cre-mediated recombination. This mutation abolishes binding to E2F1. |
