Primary Identifier | MGI:5642079 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CD2-Il23r)2Cdon |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A transgenic vector was generated with interleukin 23 receptor (Il23r) cDNA, amplified from a T helper (Th) 17 cell pool, followed by polyadenylation signal (polyA), under control of a human CD2 promoter. This construct also contains the CD2 locus control region (LCR) to increase gene expression by preventing the down-modulation of the expressed gene. Line 2 was analyzed. |