Primary Identifier | MGI:5645931 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Prickle1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An FRT site, splice acceptor, EYFP, loxP site, neomycin resistance (neo) cassette, FRT site and loxP site were inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. Cre mediated recombination removed the neo cassette and exon 2. Immunoblot analysis confirmed the absence of expression in homozygous mice. |