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Allele : Col1a1<tm1(tetO-GFP/RNAi:Sirt1)Pyc> collagen, type I, alpha 1; targeted mutation 1, Peter Y Chuang
Primary Identifier  MGI:5646012 Allele Type  Targeted
Attribute String  Knockdown, Reporter, RMCE-ready Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
description  The allele was made in KH2 cells that carry Gt(ROSA)26Sortm1(rtTA*M2)Jae and Col1a1tm13(neo/hygro*)Jae. This allele was generated with Col1a1tm13(neo/hygro*)Jae.
molecularNote  RMCE on KH2 cells inserted a cassette that contains the tetracycline promoter and a GFP fusion with a Mir30e-based short hairpin sequence targeting Sirt1 (Sirt1.688) into the 3'UTR.
  • mutations:
  • Insertion
  • synonyms:
  • Sirt1<RNAi>,
  • Col-TGM,
  • Sirt1<RNAi>,
  • Col-TGM
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1 Feature

Trail: Allele

Genome

0 Expresses

1 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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