| Primary Identifier | MGI:5646147 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Abcc9 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | LoxP sites and a neomycin selection cassette were inserted into the flanking regions of exon 5. Mice heterozygous for the targeted allele were crossed with protamine-Cre transgenic mice to remove the neomycin cassette and exon 5. Deletion of exon 5 induced a frameshift and disrupted expression of the encoded protein. Expression of both the long form and the short form of the encoded protein was affected. |
