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Allele : Pik3cb<tm1.1Jdo> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; targeted mutation 1.1,Julian Downward
Primary Identifier  MGI:5646522 Allele Type  Targeted
Attribute String  Not Specified Gene  Pik3cb
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  S205D (AGT->GAT) and K224A (AAA->GCA) point mutations were introduced to the catalytic subunit of the gene and an FRT-flanked neomycin selection cassette was inserted in intron 6. The neomycin selection cassette was excised through crosses with Tg(ACTFLPe)9205Dym deleter mice, leaving a single FRT site in intron 6/7.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • p110beta-RBD-DM,
  • p110beta-RBD-DM
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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