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Allele : Tfap2a<tm2.1Will> transcription factor AP-2, alpha; targeted mutation 2.1, Trevor Williams

Primary Identifier  MGI:5647993 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Tfap2a
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 5 and an frt-flanked neo cassette was inserted after exon 6, followed by another loxP site. RT-PCR analysis indicates that homozygotes contain only 35% of wild-type Tfap2a levels and RNA analysis indicates that the allele generates aberrant transcripts.
  • mutations:
  • Insertion
  • synonyms:
  • NEO,
  • NEO,
  • Neoflox,
  • Neoflox
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele