Primary Identifier | MGI:5647993 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph | Gene | Tfap2a |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 5 and an frt-flanked neo cassette was inserted after exon 6, followed by another loxP site. RT-PCR analysis indicates that homozygotes contain only 35% of wild-type Tfap2a levels and RNA analysis indicates that the allele generates aberrant transcripts. |