| Primary Identifier | MGI:5648123 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(E2F1-luc)1Ech |
| Strain of Origin | FVB | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human E2F1 promoter controls the expression of a firefly luciferase gene. Bioluminescence correlates with the number of tumor cells and with the loss of RB pathway necessary for transformation activity and the proliferative capacity of tumor cells. 8 founders with germline transmission were generated; three of these showed tight cell-cycle regulation of expression in vitro. |
