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Allele : Tg(tetO-AGTR1*N111G,-lacZ)1Aco transgene insertion 1, Justin Ainscough
Primary Identifier  MGI:5648211 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence, Reporter Gene  Tg(tetO-AGTR1*N111G,-lacZ)1Aco
Strain of Origin  (CBA x C57BL/6) Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  Transgenic mice with inducible cardiomyocyte-specific expression of an N111G mutant form of the human angiotensin II (Ang II) type-1 receptor (hAT1R) showed strong cardiomyocyte-specific LacZ activation in both neonatal and adult hearts, and pulmonary veins when induced. When adults were given dox, the receptor expression was repressed.
  • mutations:
  • Insertion
  • synonyms:
  • hAT1R-mut1,
  • hAT1R-mut1
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories

Trail: Allele




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