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Allele : Tg(tetO-Kras*G12D)#Rdp transgene insertion, Ronald DePinho
Primary Identifier  MGI:5648530 Allele Type  Transgenic
Attribute String  Conditional ready, Inducible, Inserted expressed sequence Gene  Tg(tetO-Kras*G12D)#Rdp
Strain of Origin  FVB/N Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The murine Kras containing the G12D mutation is under the control of the tet-operator with a lox-stop-lox cassette inserted between the promoter and the start codon of the Kras open reading frame. Expression of the mutant Kras is dependent on Cre-mediated deletion of the stop cassette. The pound symbol (#) is used when line is not specified and/or lines are pooled.
  • mutations:
  • Insertion
  • synonyms:
  • TetO_LKras<G12D>,
  • TetO_LKras<G12D>,
  • tetO_Lox-Stop-Lox-Kras<G12D>,
  • tetO_Lox-Stop-Lox-Kras<G12D>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

13 Publication categories

Trail: Allele




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