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Allele : Cdkn2a<tm1.1Lshe> cyclin dependent kinase inhibitor 2A; targeted mutation 1.1, Lanlan Shen
Primary Identifier  MGI:5660270 Allele Type  Targeted
Attribute String  Conditional ready Gene  Cdkn2a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A construct consisting of a loxP site, 140 bp cis element, an FRT flanked neo cassette and a second loxP site was inserted 1 kb upstream of the transcription start site. The cis element contains 3 DNA sequence motifs enriched in methylated promoters. Flp mediated recombination removed the neo cassette. Age-related promoter methylation is increased.
  • mutations:
  • Insertion
  • synonyms:
  • p16<cis>,
  • p16<cis>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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