| Primary Identifier | MGI:5660284 | Allele Type | Targeted |
| Gene | Yap1 | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The targeting construct was designed (by site-directed mutagenesis) to substitute a serine for an alanine at codon 112 in exon 2. A loxP-STOP-loxP (LSL) cassette was inserted between exons 1 and 2. Cre-mediated recombination removed the LSL cassette allowing conditional expression of the S112A mutation. |