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Allele : Col1a1<tm5(CAG-FGFR2_iIIIb*W290C)Kkw> collagen, type I, alpha 1; targeted mutation 5, Kwok-Kin Wong
Primary Identifier  MGI:5661327 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The chicken beta-actin (CAG) promoter, a loxP flanked STOP cassette, and human FGFR2 cDNA with the extracellular W290C domain activating mutation were inserted into the mouse collagen A1 locus . Upon cre-mediated recombination, the STOP cassette is excised promoting expression of the mutant FGFR2.
  • mutations:
  • Insertion
  • synonyms:
  • FGFR2<W290C>,
  • FGFR2<W290C>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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