Primary Identifier | MGI:5660027 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence, Reporter | Gene | Tg(tetO-PRKCG*S361G,-GFP)3Jpka |
Strain of Origin | Not Specified | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The complete coding sequence of the human PRKCG cDNA with the S361G mutation was inserted in the bidirectional pTRE-Tight-BI response plasmid containing aequorea coerulescens green fluorescent protein gene as a reporter. The S361G mutation, located in the kinase domain, is seen in families with spinocerebellar ataxia 14. Five lines were established with line 3 studied further. |