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Allele : Rasa1<tm2.1Pdk> RAS p21 protein activator 1; targeted mutation 2.1, Philip D King

Primary Identifier  MGI:5661985 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rasa1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  An R780Q mutation was inserted in exon 18 and an FRT flanked neo cassette was inserted in intron 18 via homologous recombination. Flp mediated recombination removed the neo cassette. This mutation is predicted to abrogate the ability of the protein to promote RAS hydrolysis of bound GTP.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Rasa1<R780Q>,
  • Rasa1<R780Q>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele