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Allele : Fzd10<tm1.1Nat> frizzled class receptor 10; targeted mutation 1.1, Jeremy Nathans

Primary Identifier  MGI:5688883 Allele Type  Targeted
Attribute String  Conditional ready, No functional change, Reporter Gene  Fzd10
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted within the first coding exon 5' of the initiator methionine codon, and 3' of an SV40 polyadenylation signal that was inserted immediately 3' of the 3' UTR. The following DNA segments were added immediately downstream of the 3' loxP site: (1) the coding region for human placental alkaline phosphatase (AP), and (2) a phosphoglycerate kinase (PGK)-Neo cassette flanked by FRT sites (FNF). Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Fzd10-CKO-AP,
  • Fzd10-CKO-AP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele