| Primary Identifier | MGI:5693117 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Hdac6 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| description | The prinicpal investigator has confirmed the that the original construct included loxP sites flanking exons 10-13 and an FRT-flanked neo/zeo cassette. Cre-mediated recombination removed exons 10-13. |
| molecularNote | A targeting vector was designed to insert a loxP site upstream of exon 10, an FRT-flanked neomycin resistance (neo) and zeocin (Zeo) resistance cassette, followed by a second loxP site downstream of exon 13. Cre-mediated recombination removed the floxed cassette. Immunoblot analysis of brain samples demonstrated the absence of protein, |
