Primary Identifier | MGI:5695654 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inducible, Inserted expressed sequence | Gene | Col1a1 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Induced With | doxycycline/tetracycline | Is Recombinase | false |
Is Wild Type | false |
description | C2 (Jaenisch) ES cells are derived from ES cell line v6.5. |
molecularNote | A cassette containing a CMV/tetO promoter and a human IDH2 cDNA with an R172K mutation was inserted in the 3' end of the gene. An FRT clanked selection cassette was also inserted and then removed by flp mediated recombination. |