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Allele : Pcdh15<tm2.1Mll> protocadherin 15; targeted mutation 2.1 Ulrich Muller

Primary Identifier  MGI:5697806 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Pcdh15
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin selection cassette replaced exon 38. The neo cassette was subsequently removed by crossing the mice carrying the targeted allele to Flp-deleter mice. qPCR and in situ hybridization analyses of P1 homozygous mutant mice confirmed that expression of the CD2 isoform is abolished while expression of isoforms CD1 and CD3 is maintained.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • deltaCD2,
  • PCDH15-deltaCD2,
  • exon38KO,
  • deltaCD2,
  • PCDH15-deltaCD2,
  • exon38KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele