| Primary Identifier | MGI:5699182 | Allele Type | Targeted |
| Gene | Prkcd | Transmission | Germline |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette downstream of exon 13 of the gene. A point mutation, M425A, is introduced in exon 13, which encodes a key residue for determining the selectivity of PKC inhibitors. Cre-mediated recombination removed the floxed neo cassette. |
