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Allele : Alk<tm1Dgen> anaplastic lymphoma kinase; targeted mutation 1, Deltagen

Primary Identifier  MGI:5700373 Allele Type  Targeted
Attribute String  Null/knockout Gene  Alk
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence from exon 22, containing 35bp coding for the protein, was replaced by a IRES-beta-gal-neomycin selection cassette. This mutation is predicted to lead to premature transcript termination and deletion of the transmembrane and kinase domains in the encoded protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele