| Primary Identifier | MGI:5698834 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Mapt |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP-flanked neomycin selection cassette replaced a genomic fragment containing exon 10. The neomycin cassette was removed via Cre-mediated recombination. This allele mis-expresses the 3R-tau isoform after P18 in heterozygous and homozygous mice, when it is not seen in wild-type mice. 4R-tau isoform expression is unaffected. |
