| Primary Identifier | MGI:5698695 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Ret |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 14 and 15 and an FRT-flanked neo cassette are flanked by loxP sites. A missense mutation in exon 15 changes valine 805 to alanine. This mutation is silent but sensitizes the protein to chemical inhibition of its kinase activity. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 14 and 15 floxed. |
