| Primary Identifier | MGI:5704313 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Fgf13 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| description | Phenotypic Similarity to Human Syndrome: Generalized Epilepsy with Febrile Seizures Plus J:222555. |
| molecularNote | A targeting vector was designed to remove the 3' region of exon 2 and a 600 bp intronic sequence common to all isoforms and replace it with a neomycin-resistance cassette and an in-frame stop codon after the last codon of the remaining exon 2. qPCR analysis of hippocampal and cortical mRNA from 50 day old heterozygous females indicates an approximate 50% reduction of mRNA and Western blot confirmed an approximate 50% reduction in protein. |
