Primary Identifier | MGI:5705123 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Prnp-ATXN7*92Q)1963Als |
Strain of Origin | (C57BL/6J x C3H/HeJ)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The coding region of the human gene containing 92 CAG repeats is under the control of the murine prion protein promoter. N-terminal FLAG and C-terminal c-myc epitope tags were also added. Western blot analysis confirmed the expression of the full-length protein in the cerebellum and retina. |