| Primary Identifier | MGI:5705324 | Allele Type | Targeted |
| Gene | Alk | Transmission | Germline |
| Strain of Origin | 129S2/SvPas | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 25 was replaced with one in which a point mutation that results in the amino acid substitution of glutamine for arginine at position 1279. This mutation corresponds to the R1275 identified in patients with neuroblastoma. Cre-mediated recombination removed the neomycin resistance cassette inserted downstream of the modified exon. |
