Primary Identifier | MGI:5707003 | Allele Type | Targeted |
Gene | Chrnb2 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 3 was replaced with one in which a point mutation results in the amino acid substitution of leucine for valine at position 287 (V287L). Cre-mediated recombination removed the floxed neomycin selection inserted downstream of the modified exon. |