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Allele : Usp18<tm1.1Kpk> ubiquitin specific peptidase 18; targeted mutation 1.1, Klaus-Peter Knobeloch
Primary Identifier  MGI:5705585 Allele Type  Targeted
Gene  Usp18 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  An FRT flanked selection cassette was inserted in intron 2 and the codon in exon 3 for Cys61 5'-TGT-3' was mutated to 5-GCT-3' encoding alanine via homologous recombination. Flp mediated recombination removed the selection cassette. The mutation in exon 3 disrupts the isopeptidase activity of the protein. However regulatory properties of the protein are intact.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • USP18<C61A>,
  • USP18<C61A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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11 Publication categories

Trail: Allele




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