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Allele : Plp2<tm1Dva> proteolipid protein 2; targeted mutation 1, David Valle

Primary Identifier  MGI:5707490 Allele Type  Targeted
Attribute String  Null/knockout Gene  Plp2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A LacZ-neo cassette was inserted into exon 1, six codons downstream of the translational start site. Northern blot analysis revealed absence of transcript in primary neurons isolated from hemizygous mutant males. Western blot analysis confirmed the absence of protein expression in mutant retinal tissue.
  • mutations:
  • Insertion
  • synonyms:
  • Plp2<->,
  • Plp2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele