| Primary Identifier | MGI:5705517 | Allele Type | Targeted |
| Attribute String | Dominant negative | Gene | Gabra1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A missense mutation was generated in exon 9 by mutating the GCC codon with GAC to encode A322D followed with neomycin cassette in intron 9. Cre-mediated recombination removed the neomycin cassette. Western blot analysis at P15 shows that homozygotes express 6 +/- 3% of the amount of protein as in wild-type mice. |
