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Allele : Tg(Sftpc-Grem1)105Mmyl transgene insertion 105, Marjukka Myllarniemi
Primary Identifier  MGI:5707177 Allele Type  Transgenic
Attribute String  Conditional ready, Inserted expressed sequence Gene  Tg(Sftpc-Grem1)105Mmyl
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene contains the surfactant associated protein C (Sftpc) promoter followed by a loxP-flanked neomycin resistance cassette with a strong translation termination (STOP) signal and the gremlin 1, DAN family BMP antagonist (Grem1) coding sequence. Deletion of the floxed sequence by Cre recombinase in transgenic mice results in Grem1 expression in lung type II epithelial cells.
  • mutations:
  • Insertion
  • synonyms:
  • SPC-lox-gremlin1,
  • SPC-lox-gremlin1
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