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Allele : Gt(ROSA)26Sor<tm1(tetO-tdTomato,-BRAF*)Mmok> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Markus Morkel
Primary Identifier  MGI:5707503 Allele Type  Targeted
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Induced With  doxycycline/tetracycline Is Recombinase  false
Is Wild Type  false
molecularNote  Recombination using Gt(ROSA)26Sortm2Bgh replaced the hygromycin resistance cassette is replaced with tetracycline response element driving inducible expression of a tdTomato reporter gene, 2A peptide sequence and a human BRAF cDNA with the point mutation that results in the amino acid substitution of lysine for valine at position 600 (V600K) followed by a polyadenylation sequence.
  • mutations:
  • Insertion
  • synonyms:
  • tdTomato-BRAF<V600K>,
  • tdTomato-BRAF<V600K>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele




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