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Allele : Scn8a<tm1.1Aesc> sodium channel, voltage-gated, type VIII, alpha; targeted mutation 1.1, Andrew Escayg
Primary Identifier  MGI:5749693 Allele Type  Targeted
Gene  Scn8a Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  The targeting construct introduced a mutation that results in the amino acid substitution of histidine for arginine at position 1648 (R1648H) and two additional silent substitutions in exon 26. Flp-mediated recombination removed the neomycin resistance cassette.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Scn8a R1627H,
  • Scn8a<RH>,
  • Scn8a<RH>,
  • Scn8a R1627H
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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