Primary Identifier | MGI:5751992 | Allele Type | Targeted |
Gene | Mov10l1 | Transmission | Germline |
Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Codon 778 in exon 17 was mutated from AAG (lysine to GCG (alanine) and a floxed neo cassette was inserted in intron 17 via homologous recombination. Cre mediated recombination removed the neo cassette. This mutations disrupts RNA helicase activity. |